Integration of hyaluronic acid into biodegradable thread matrices

Biodegradable threads incorporate biocompatible polymers and hyaluronic acid (HA), with the aim of not only repositioning soft tissues, but also promoting dermal regeneration.

This isn’t a new thread. It’s about positioning your clinic at the forefront of regenerative aesthetic dermatology.
The integration of HA into biodegradable thread matrices with NAMICA technology isn’t an improvement, it’s a revolution. It allows you to deliver results that the competition can’t: an immediate lift with a visible long-term improvement in skin quality.

Thread lift techniques have evolved significantly, from simple mechanical suspension methods to sophisticated bioactive platforms.

Injectable dermal fillers, including hyaluronic acid, polylactic acid, and calcium hydroxyapatite, restore volume and contour with immediate aesthetic impact and minimal invasiveness.

Lifting with biodegradable threads and hyaluronic acid

Thread lifting technologies have emerged as a minimally invasive, yet biologically active, approach to aesthetic correction.

Originally developed for mechanical tissue suspension, modern thread lifting systems now serve as multifunctional platforms that integrate structural support with regenerative signaling. By leveraging advances in polymer chemistry, bioresorbable scaffolds, and hyaluronic acid (HA) delivery, next-generation thread lifting systems are designed to modulate dermal remodeling and provide immediate lifting effects.

The Future of Dermoesthetics Has Arrived: NAMICA Technology.

Thread lifting technologies have undergone substantial innovation. These devices have evolved from rudimentary mechanical lifting tools to multifunctional platforms capable of both structural and regenerative effects.

Thread lifting implants composed of HA-functionalized P(LA/CL) copolymers are of particular clinical interest. These hybrid materials offer a dual benefit: immediate biomechanical support and prolonged stimulation of dermal remodeling. The incorporation of controlled-release systems represents a crucial milestone, as it allows for sustained HA bioavailability and improved tissue integration.

What is NAMICA technology?

Developed by Aptos, NAMICA technology seeks to improve the delivery and efficacy of hyaluronic acid (HA) by encapsulating the molecules. One of the key challenges has been delivering HA precisely to the target area without causing the molecules to lose efficacy or degrade too quickly. NAMICA technology successfully addressed this challenge, unleashing HA’s full potential.

25 Times More Effective: HA’s Liberation Revolution.

  • Encapsulation of HA molecules: NAMICA technology coats HA molecules of various sizes using the same absorbable material as the thread itself, polylactic acid (PLA). This coating facilitates the controlled release of HA at the injection sites.
  • Targeted delivery: The encapsulated HA molecules are designed to be released precisely at the intended site, without loss or premature degradation during the injection process.
  • Controlled release: Different sizes of HA molecules have different release rates. This gradual release ensures prolonged HA secretion and continuous benefits for the skin.
  • Enhanced collagen production: The controlled release of HA not only maintains skin hydration but also stimulates collagen production.
  • Long-lasting effects: Treatments with NAMICA technology can provide up to six months of active HA release and more than a year of visible results. This efficiency is due to the technology’s ability to release 25 times more HA than traditional methods.

Six Months of Active Release. One Year of Visible Results.

Preclinical studies have provided strong evidence of the regenerative potential of these advanced thread systems. Initial in vivo data highlight favorable histological results, such as enhanced neocollagenesis and extracellular matrix (ECM) reorganization. This underscores their biostimulatory efficacy.

The integration of HA into biodegradable thread matrices represents a paradigm shift in the field of aesthetic dermatology.

By combining immediate mechanical lifting with sustained dermal regeneration, these next-generation implants offer a promising minimally invasive strategy for facial rejuvenation.

This technology could play a pivotal role in the development of individualized biomimetic interventions for age-related skin restoration.

Active Encapsulation Giants with Biodegradable Matrices

The development of encapsulation technologies and biodegradable matrices is essential for advanced cosmetics, enabling the sustained release of active ingredients. Leading global companies are leading the way in this field:


Givaudan Active Beauty (Switzerland): Innovation in Intelligent Encapsulation

Givaudan, known for its leadership in fragrances, also excels in encapsulation technologies and biodegradable matrices for functional cosmetics.

Its focus on intelligent encapsulation is manifested in systems such as Unispheres™, biodegradable microspheres that release active ingredients upon contact with the skin.

In addition, they develop customized carriers that allow for the prolonged release of key ingredients such as hyaluronic acid, antioxidants, or peptides.

Among their notable technologies are S3D® HydraSplash and S3D® Lumière Noire, which combine encapsulated active ingredients with compelling sensorial storytelling. They also promote Green & Blue Biotechnology, leveraging marine and plant resources to create sustainable and functional ingredients. This allows cosmetic brands to launch products with claims such as “extended release,” “second-skin effect,” or “smart ritual” without the need to develop these technologies in-house.

Lubrizol Life Science (USA): Biodegradable Polymers and Sustainability Real

Lubrizol is a global leader in functional and biodegradable polymers for personal care, with a strong presence in formulations incorporating hyaluronic acid. Its biodegradable polymers, such as Carbopol® BioSense, are designed for light emulsions that offer controlled release and excellent sensoriality.

Its matrices are compatible with HA, allowing its delivery in both leave-on and rinse-off systems, maintaining its stability and efficacy.

A fundamental pillar of Lubrizol is true sustainability, creating ingredients with low environmental impact, eco-designed processes, and certified biodegradability.

At key events such as In-Cosmetics Global, they present solutions that combine superior technical performance with a “green storytelling.” This is ideal for brands seeking to differentiate themselves with claims such as “clean biotechnology,” “conscious texture,” or “smart-release encapsulated active ingredients.”

RAHN AG (Switzerland): Controlled Release Systems with HA

RAHN AG combines deep chemical expertise with advanced cosmetic formulation, focusing on controlled-release systems incorporating hyaluronic acid. They develop biodegradable matrices that allow for gradual HA dosing, perfect for anti-aging and soothing products.

Its Cosmetic Actives line includes functional ingredients that can be integrated into various formulations such as gels, creams, and serums, ensuring sustained release. Its technical approach is based on working with biocompatible polymers and carriers that optimize dermal penetration, collaborating closely with laboratories to validate the efficacy and stability of its solutions. RAHN AG is perfect for brands seeking claims such as “long-lasting effect,” “Swiss smart release technology,” or “deep care without residue.”
A Future Driven by Innovation

Both NAMICA technology in dermo-aesthetics and the advanced encapsulation solutions and biodegradable matrices from Givaudan, Lubrizol, and RAHN AG are leading the way in the industry.

These innovations not only offer superior efficacy and long-lasting results, but also pave the way for more sustainable and intelligent cosmetics, capable of delivering unparalleled benefits to consumers.

The future of beauty lies in the science of controlled release and a commitment to regenerative innovation.

Don’t settle for reading the news. 

Access the intelligence that allows you to create it.

Join the Private Circle and become part of B2B Market Intelligence.

Acceder al Directorio de Empresas

VITAMINA D MultiMoist CLR™

vitamina D con MultiMoist CLR

Articulos Relacionados

Este sitio web utiliza cookies para mejorar su experiencia. Asumiremos que está de acuerdo con esto, pero puede optar por no participar si lo desea. Acepto LEER MÁS